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Q: What are your thoughts on reported connections between acne treatments tetracycline/minocycline and hair loss? I began to experience mild acne a little less than a year ago and was prescribed tetracycline. After a couple of months the acne cleared, but I also noticed significant thinning in the temple areas. I stopped taking the medication over 5 months ago and there's been no regrowth. My dermatologist told me there was no connection, but I had no lifestyle changes besides the medication to cause the hair loss.

A: I am asked similar questions frequently. Acne is due to the action of testosterone on the skin. Female alopecia (hair loss) is also usually due to testosterone action. Testosterone can also cause hirsutism (excessive or unwanted facial and body hair). For this reason, many women who have one of the three problems (acne, hirsutism and alopecia) have one or both of the other problems. Accutane (isotretinoin) is the only acne medication which might contribute to alopecia. Antibiotics and topicals will not. Most birth control pills, if they have any effect, will help alopecia somewhat, but there is suspicion that those containing the progestin levonorgestrel could contribute to alopecia. However no one should stop or change her medications without discussing with her physician.

So to answer your question directly, when a woman with acne or unwanted hair has alopecia, it is likely that the hair loss is due to the underlying condition rather than treatment.

Very few medications, other than cancer chemotherapy, cause hair loss. As discussed in my web article on alopecia, even if testosterone is normal it can still cause female hair loss.

Hope this is helpful.


Geoffrey Redmond, MD

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